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	<title>journalClub &#187; cardiovascular</title>
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	<description>Comments on the medical literature</description>
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		<title>Multidetector spiral CT for PE</title>
		<link>http://www.journalclub.org/2005/05/03/n59</link>
		<comments>http://www.journalclub.org/2005/05/03/n59#comments</comments>
		<pubDate>Tue, 03 May 2005 17:51:30 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[imaging]]></category>
		<category><![CDATA[medical]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/04/28/n59</guid>
		<description><![CDATA[Last week&#8217;s NEJM has an article, from Switzerland and France, on multidetector-row computed tomography in suspected pulmonary embolism. Rationale The authors state that first-generation, single-detector, spiral CT scanning is quite specific (90%) but not very sensitive (70%) for detecting pulmonary emboli. In two previous studies by their group, negative CT scans were contradicted by positive [...]]]></description>
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		<slash:comments>1</slash:comments>
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		<title>Cardiac resynchronization in heart failure</title>
		<link>http://www.journalclub.org/2005/04/16/n58</link>
		<comments>http://www.journalclub.org/2005/04/16/n58#comments</comments>
		<pubDate>Sun, 17 Apr 2005 00:11:28 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[medical]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/04/16/n58</guid>
		<description><![CDATA[Patients with heart failure often have intraventricular conduction delays (such as bundle branch blocks), which cause the ventricles to contract dyssynchronously, in an inefficient manner. This is the rationale behind the implantation of biventricular pacing devices to restore synchrony. The effect of cardiac resynchronization on morbidity and mortality in heart failure, in this week&#8217;s NEJM, [...]]]></description>
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		<slash:comments>0</slash:comments>
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		<title>Intensive lipid-lowering therapy</title>
		<link>http://www.journalclub.org/2005/04/09/n57</link>
		<comments>http://www.journalclub.org/2005/04/09/n57#comments</comments>
		<pubDate>Sun, 10 Apr 2005 02:42:41 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[medical]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/04/09/n57</guid>
		<description><![CDATA[[Back after a two-month hiatus, due to busy practice, vacation, and time spent/wasted playing with video editing software and a new camcorder...] In this week&#8217;s NEJM, Intensive lipid lowering with atorvastatin in patients with stable coronary disease makes an argument in favor of reducing LDL cholesterol levels for secondary prevention to lower than the current [...]]]></description>
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		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Take two ximelegatran and call me in the morning</title>
		<link>http://www.journalclub.org/2005/02/13/n56</link>
		<comments>http://www.journalclub.org/2005/02/13/n56#comments</comments>
		<pubDate>Mon, 14 Feb 2005 02:06:11 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/02/09/n56</guid>
		<description><![CDATA[[Addendum, 2/14/05: as has been pointed out by commenters, ximelagatran was turned down for approval by an FDA panel in September, 2004, because of concerns about hepato-toxicity. Whether it will ever be marketed in the US is very much in doubt. The following post has been slightly edited with this in mind.] Coumadin is such [...]]]></description>
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		<slash:comments>3</slash:comments>
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		<title>Women and non-smokers need not apply</title>
		<link>http://www.journalclub.org/2005/02/01/n51</link>
		<comments>http://www.journalclub.org/2005/02/01/n51#comments</comments>
		<pubDate>Wed, 02 Feb 2005 03:59:22 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[medical]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/02/01/n51</guid>
		<description><![CDATA[The new USPSTF recommendations concerning screening for AAA appear in this week&#8217;s Annals of Internal Medicine, and are being quoted in the press. Bottom-line: screen men who have ever smoked, once between the ages of 65 and 75. Under 65: too low morbidity/mortality to make screening worthwhile Over 75: too high co-morbidities to make a [...]]]></description>
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		<slash:comments>1</slash:comments>
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		<title>Vioxx and the 140,000 MI&#8217;s</title>
		<link>http://www.journalclub.org/2005/01/25/n50</link>
		<comments>http://www.journalclub.org/2005/01/25/n50#comments</comments>
		<pubDate>Wed, 26 Jan 2005 03:49:22 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[medico-legal]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/01/25/n50</guid>
		<description><![CDATA[As I previously noted here, a study by Graham et al, examining the cardiovascular risks of Vioxx, was being considered for publication in the Lancet when it was prematurely published on the FDA&#8217;s website, much to the Lancet&#8217;s dismay. Today, that same study, with some modifications, has been published online at the Lancet. It is [...]]]></description>
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		<slash:comments>2</slash:comments>
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		<title>Aspirin vs. Plavix after upper GI bleeding</title>
		<link>http://www.journalclub.org/2005/01/24/n49</link>
		<comments>http://www.journalclub.org/2005/01/24/n49#comments</comments>
		<pubDate>Mon, 24 Jan 2005 17:14:41 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>
		<category><![CDATA[gastrointestinal]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/01/24/n49</guid>
		<description><![CDATA[What a frustrating paper. In last week&#8217;s NEJM is a study from the Prince of Wales Hospital in Hong Kong looking at clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. More precisely, the authors studied patients who had been on 325 mg aspirin or less, who presented with upper GI bleeding and who [...]]]></description>
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		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>More on CRP</title>
		<link>http://www.journalclub.org/2005/01/07/n47</link>
		<comments>http://www.journalclub.org/2005/01/07/n47#comments</comments>
		<pubDate>Fri, 07 Jan 2005 12:28:37 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/01/07/n47</guid>
		<description><![CDATA[The two NEJM articles on C-Reactive Protein which I commented on yesterday have raised quite a stir. Gina Kolata&#8217;s headline in the NY Times that I saw in my print paper yesterday blared: &#8220;Two Studies Suggest a Protein Has a Big Role in Heart Disease&#8220;. Today, I went to the Times website to find the [...]]]></description>
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		<slash:comments>1</slash:comments>
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		<title>CRP and statins</title>
		<link>http://www.journalclub.org/2005/01/06/n44</link>
		<comments>http://www.journalclub.org/2005/01/06/n44#comments</comments>
		<pubDate>Thu, 06 Jan 2005 04:01:11 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/01/05/n44</guid>
		<description><![CDATA[Today&#8217;s NEJM has two articles on statin therapy and achieved LDL and CRP levels in relation to coronary disease. The first article, from Harvard, is a substudy of the Pravastatin or Atorvastatin Evaluation and Infection Therapy &#8211; Thrombolysis in Myocardial Infarction 22 study (I challenge you to reread the name of this study once and [...]]]></description>
		<wfw:commentRss>http://www.journalclub.org/2005/01/06/n44/feed</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Coronary revascularization before vascular surgery</title>
		<link>http://www.journalclub.org/2005/01/03/n41</link>
		<comments>http://www.journalclub.org/2005/01/03/n41#comments</comments>
		<pubDate>Mon, 03 Jan 2005 19:35:00 +0000</pubDate>
		<dc:creator>mjmd</dc:creator>
				<category><![CDATA[cardiovascular]]></category>

		<guid isPermaLink="false">http://www.journalclub.org/2005/01/03/n41</guid>
		<description><![CDATA[Patients undergoing vascular surgery are at higher risk for cardiovascular events. Despite published guidelines, the exact approach to pre-operative cardiac evaluation for these patients varies significantly. The report of a VA cooperative study in last week&#8217;s NEJM looked at the value of prophylactic coronary-artery revascularization before elective major vascular surgery. Patients undergoing elective AAA repair [...]]]></description>
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		<slash:comments>0</slash:comments>
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